Bioinformatics, non-coding RNAs and its possible application in personalized medicine.

Abstract excerpt

Non-coding RNAs are important actors in human biology. A massive amount of data has been created and manipulated, and important findings have been extracted thanks in part to bioinformatics approaches and consequent experimental validation; many of these results are for a specific class of non-coding RNAs, the microRNAs (miRNAs), that are important regulators of gene expression although their transcriptional...

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