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The clonal architecture and tumour microenvironment of breast cancers are shaped by neoadjuvant chemotherapy

2019-01-01

Abstract excerpt

Neoadjuvant chemotherapy has become standard practice in patients with high-risk early breast cancer as it improves rates of breast conservation surgery and enables prediction of recurrence and survival by using response to treatment as a surrogate. Previous studies have focused on generating molecular datasets to develop prediction models of response, though little is known on how tumours and their microenvironme...

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Literature Corpus work
2ffeacf2-629e-5023-96c3-8368476fd97f
DOI
10.17863/cam.37645
Open publication

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