Article

Polygenic susceptibility to dilated cardiomyopathy underlies peripartum, alcohol-induced, and cancer therapy-related cardiomyopathies

2025-02-23

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Rare (monogenic) variants linked to non-ischemic dilated cardiomyopathy (DCM) are enriched among individuals with peripartum (PPCM), alcohol-induced (ALCM), and cancer therapy-related (CCM) cardiomyopathies, but are present in less than 15% of cases. Whether a common variant (polygenic) predisposition to DCM also pervades these secondary cardiomyopathies remains unclear. <h4>M...

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Literature Corpus work: 2f6d7408-e665-5062-b9aa-50edc6eddc5c
DOI: 10.1101/2025.02.17.25321705

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