Article

cGAS-STING signaling regulates control of microglia polarization in cerebral ischemic stroke

2020-02-25

Abstract excerpt

<title>Abstract</title> <p>Background Cerebral ischemic stroke is a highly debilitating disease, in which inflammation is well document to play a pivotal role in its pathophysiology. Microglia are the the major immuncompetent cells of the brain involved in different neuropathologies. Recent discovery of cyclic GMP-AMP synthase(cGAS) activation and its induction of the downstream signaling protein stimulator of in...

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Literature Corpus work: 2f537d54-745b-5c49-9499-4475eb408fbd
DOI: 10.21203/rs.2.24452/v1

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