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GeneDART: Extending gene coverage in image-based spatial transcriptomics by deep learning-based domain adaptation with barcode-based RNA-sequencing data

2023-02-08

Abstract excerpt

Spatial transcriptomics (ST) technologies provide comprehensive biological insights regarding cell-cell interactions and peri-cellular microenvironments. ST technologies are divided into two categories: imaging-based (I-B) and barcode-based (B-B). I-B ST technologies provide high resolution and sensitivity but have limited gene coverage. B-B ST technologies can analyze the whole transcriptome but have lower spatia...

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Literature Corpus work: f8730b4d-8b48-5750-abaa-7d3d302b01d2
DOI: 10.1101/2023.02.07.527488

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