Article

Pixel2Gene enables histology-guided reconstruction and prediction of spatial gene expression

2026-02-23

Abstract excerpt

Advances in spatial transcriptomics (ST) have fundamentally transformed our understanding of tissue biology by enabling gene expression profiling within intact spatial contexts and uncovering tissue organization and microenvironmental interactions. However, current high-resolution ST platforms remain constrained by high costs, limited tissue coverage, and technical artifacts, often yielding noisy, sparse, and inco...

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Literature Corpus work: 7429c79c-4dd8-5281-b056-914952446bf6
DOI: 10.64898/2026.02.21.707168

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