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Improved Graph-Based Antibody-Aware Epitope Prediction with Protein Language Model-Based Embeddings

2025-02-17

Abstract excerpt

The accurate identification of B-cell epitopes is critical in antibody design, diagnostics, and immunotherapies. Many in silico approaches have recently been proposed to predict epitopes, but these approaches struggle primarily because of the variational and conformational nature of epitopes. However, deep learning-based approaches have recently shown great promise in achieving better performance at the epitope p...

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Literature Corpus work
2f3fca55-13a6-56c9-b8fe-3ee8b1c8de86
DOI
10.1101/2025.02.12.637989
Open publication

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Improved Graph-Based Antibody-Aware Epitope Prediction with Protein Language Model-Based EmbeddingsDOI 10.1101/2025.02.12.637989
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