Article

Complementary value of molecular, phenotypic and functional aging biomarkers in dementia prediction

2024-06-24

Abstract excerpt

DNA methylation age (MA), brain age (BA), and frailty index (FI) are putative aging biomarkers linked to dementia risk. We investigated their relationship and combined potential for prediction of stages of cognitive impairment and future risk of dementia using the ADNI database. Of several MA algorithms, DunedinPACE had the strongest association with neuropsychological tests and was included alongside BA and FI in...

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Literature Corpus work: 2ef88d80-47db-5f3b-a61c-29d3f7bb59d5
DOI: 10.1101/2024.06.23.24309078

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