Article

Disruption of the epigenetic regulator BAP1 drives chromatin remodeling leading to the emergence of cells with breast cancer stem cell properties and aberrant glycosylation

2024-12-13

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Epigenetic regulator genes play critical roles in controlling cell identity and are frequently disrupted in breast cancers, suggesting a key driver role in this disease and its associated phenotypes. However, specific epigenetic drivers (epidrivers) of mammary cell plasticity and their mechanistic contributions to this phenotype are poorly characterized. <h4>Methods</h4> To...

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Literature Corpus work: 2ee1bcd9-b9e7-503b-b6e9-074882a4ca64
DOI: 10.1101/2024.12.12.628129

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Disruption of the epigenetic regulator BAP1 drives chromatin remodeling leading to the emergence of cells with breast cancer stem cell properties and aberrant glycosylationDOI 10.1101/2024.12.12.628129Read

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