Article

Biofabrication of a filtration barrier by integrating electrospun membranes and flow in a glomerular co-culture

2024-12-09

Abstract excerpt

The glomerulus is the functional unit of the kidney, where urine is filtered from blood. This process happens through the glomerular filtration barrier (GFB) which is composed of glomerular endothelial cells, podocytes, and glomerular basement membrane (GBM). Damage to any component of GFB results in failure of the barrier’s function, causing proteinuria that can lead to end-stage kidney failure. There is a high n...

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Literature Corpus work: 2eaed68a-0887-5181-97dc-d5ba1dab39f9
DOI: 10.1101/2024.12.05.626949

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