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Genome-wide association analyses reveal susceptibility variants linked to Parkinson’s disease in the South African population using inferred global and local ancestry

2025-08-02

Abstract excerpt

Genome-wide association studies (GWAS) have been successful in identifying over 100 loci associated with Parkinson’s disease (PD) susceptibility. However, the majority of these studies have focused on European cohorts with few including diverse ancestries. Using genotyped and imputed data from 691 South African PD cases and 826 controls, we conducted a conventional GWAS, two local ancestry GWAS (LA-GWAS) approache...

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Literature Corpus work
2e9e8e71-b6d5-563c-bb7d-1a0f4187ff4b
DOI
10.1101/2025.08.01.25331910
Open publication

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Genome-wide association analyses reveal susceptibility variants linked to Parkinson’s disease in the South African population using inferred global and local ancestryDOI 10.1101/2025.08.01.25331910
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