Article

Hyperglycemia induces histological abnormalities and dysregulates angiotensin-converting enzymes and inflammatory signaling in zebrafish brain: Possible relationship with memory impairment

2025-02-04

Abstract excerpt

<title>Abstract</title> <p>Dysregulation of renin-angiotensin system (RAS), through the actions of angiotensin-converting enzymes significantly impacts inflammatory responses. Recent studies have demonstrated the relevance of RAS in Coronavirus Disease 2019 (COVID-19), where outcomes worsen in diabetic patients. We investigate the effects of hyperglycemia on RAS components and inflammatory gene expression in adul...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2e866242-1d64-5b75-a592-e0609c89e837
DOI: 10.21203/rs.3.rs-5783801/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Hyperglycemia induces histological abnormalities and dysregulates angiotensin-converting enzymes and inflammatory signaling in zebrafish brain: Possible relationship with memory impairmentDOI 10.21203/rs.3.rs-5783801/v1Read

Zebrafish: A New Promise to Study the Impact of Metabolic Disorders on the BrainSemantic proximity Read

Hyperglycemia induces memory impairment linked to increased acetylcholinesterase activity in zebrafish (Danio rerio)Semantic proximity Read

Induction of hyperglycaemia in zebrafish (Danio rerio) leads to morphological changes in the retinaSemantic proximity Read

Islet Endothelial Activation and Oxidative Stress Gene Expression Is Reduced by IL-1Ra Treatment in the Type 2 Diabetic GK RatSemantic proximity Read

Association Between Stress Hyperglycemia Ratio and Early Neurological Deterioration After Acute Ischemic Stroke: A Retrospective Cohort StudySemantic proximity Read

ACE2/ANG-(1-7)/Mas receptor axis activation prevents inflammation and improves cognitive functions in streptozotocin induced rat model of Alzheimer's disease-like phenotypes.Semantic proximity Read

TLR2 knockout protects against diabetes-mediated changes in cerebral perfusion and cognitive deficits.Semantic proximity Read

Jnk1 and Downstream Signalling Hubs Regulate Anxiety-like Behaviours in a Zebrafish Larvae Phenotypic ScreenSemantic proximity Read

Chronic kidney disease promotes anxiety susceptibility through an angiotensin II–central amygdala axisSemantic proximity Read

High Sucrose Diets Contribute to Brain Angiopathy with Impaired Glucose Uptake, and Psychosis-related Higher Brain Dysfunctions in MiceSemantic proximity Read

JNK1 And Downstream Signalling Hubs Regulate Anxiety-Like Behaviours In A Zebrafish Larvae Phenotypic ScreenSemantic proximity Read

Hippocampal microRNA-132 mediates stress-inducible cognitive deficits through its acetylcholinesterase targetSemantic proximity Read