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Article

A Mendelian randomization study of telomere length and blood-cell traits.

Scientific reports - 22 Jul 2020

Adams Charleen D, Boutwell Brian B

Abstract excerpt

Whether telomere attrition reducing proliferative reserve in blood-cell progenitors is causal has important public-health implications. Mendelian randomization (MR) is an analytic technique using germline genetic variants as instrumental variables. If certain assumptions are met, estimates from MR should be free from most environmental sources of confounding and reverse causation. Here, two-sample MR is performed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32699327
DOI: 10.1038/s41598-020-68786-6
PMCID: PMC7376238

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