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Article

Impact of serum 25-hydroxyvitamin D 25(OH) on telomere attrition: A Mendelian Randomization study.

Clinical nutrition (Edinburgh, Scotland) - 1 Sept 2020

Mazidi Mohsen, Mikhailidis Dimitri P, Banach Maciej, Dehghan Abbas

Abstract excerpt

BACKGROUND: Conventional observational studies have suggested that 25-hydroxyvitamin D (25(OH)D) is inversely associated with telomere shortening. We aimed to apply two-sample Mendelian randomization (MR) to assess the causal association between serum 25(OH) D and telomere length (TL). METHODS: MR was implemented by using summary-level data from the largest genome-wide association studies (GWAS) on vitamin D...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31902602
DOI: 10.1016/j.clnu.2019.12.008

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