Establishment of A Piglet Model for Peritoneal Metastasis of Ovarian Cancer

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> A piglet model for peritoneal metastasis (PM) of ovarian cancer was developed. It will contribute to the establishment of innovative chemotherapeutical and surgical strategies without any limitation of rodent models.<bold>Methods:</bold> A total of 12 four- to five-week-old piglets of 7 to 8 kg were used. Two phases of ovarian cancer cell injections were perform...

Topics

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• Adenomatous Polyposis Coli Protein
• Disease Models, Animal
• Genetic Engineering
• Mice
• Molecular Targeted Therapy
• Mutation
• Neoplasms
• Tumor Suppressor Protein p53

Identifiers and source

Literature Corpus work

2de3f5aa-54ab-5a3d-8468-6af56699b145

DOI

10.21203/rs.3.rs-806069/v1