Article

Systematic mapping of bacteriophage gene essentiality with HIDEN‑SEQ

2025-11-20

Abstract excerpt

The constant arms race of bacteriophages and their bacterial hosts has inspired major breakthroughs in biotechnology and shaped phages as fierce predators with great clinical potential to fight multidrug-resistant bacterial pathogens. However, the vast amount of genomic 'dark matter' composed of genes of unknown function in phage genomes remains a major obstacle for the molecular understanding of phage-host intera...

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Literature Corpus work: 2d8d2f6d-df4b-577e-a13f-0d9f8536c4eb
DOI: 10.1101/2025.11.20.689424

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