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Article

Chronic exposure to PFAS triggers systems-level cellular reprogramming independent of their bioaccumulation

2025-07-07

Abstract excerpt

Per- and polyfluoroalkyl substances (PFAS), or “forever chemicals,” are linked to metabolic, immune, and neurotoxic disorders, yet their long-term cellular effects remain unclear. Using a 24-week chronic exposure model with non-transformed human epithelial cells, we examined responses to low, environmentally relevant concentrations of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS). Integrat...

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Literature Corpus work
2d7d0698-ae76-5c58-8d59-be6d704ce3c3
DOI
10.1101/2025.07.03.662990
Open publication

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Chronic exposure to PFAS triggers systems-level cellular reprogramming independent of their bioaccumulationDOI 10.1101/2025.07.03.662990
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