Article
Body Mass Index, Genetic Susceptibility, and Risk of Complications Among Individuals with Crohn's Disease.
Inflammatory bowel diseases - 1 Oct 2015
Pringle Patricia L, Stewart Kathleen O, Peloquin Joanna M, Sturgeon Holly C, Nguyen Deanna, Sauk Jenny, Garber John J, Yajnik Vijay, Ananthakrishnan Ashwin N, Chan Andrew T, Xavier Ramnik J, Khalili Hamed
Abstract excerpt
BACKGROUND: Obesity is associated with systemic and intestine-specific inflammation and alterations in gut microbiota, which in turn impact mucosal immunity. Nonetheless, a specific role of obesity and its interaction with genetics in the progression of Crohn's disease (CD) is unclear. METHODS: We conducted a cross-sectional study of patients with CD enrolled in Prospective Registry in Inflammatory Bowel Disease...
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