Article
Structure-guided metagenome mining to tap microbial functional diversity.
Current opinion in microbiology - 1 Dec 2023
Robinson Serina L
Abstract excerpt
Scientists now have access to millions of accurate three-dimensional (3D) models of protein structures. How do we leverage 3D structural models to learn about microbial functions encoded in metagenomes? Here, we review recent developments using protein structural features to mine metagenomes from diverse environments ranging from the human gut to soil and ocean viromes. We compare 3D protein structural methods to...
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