Article

Microarray Profiling in Fibrogenesis Imperfecta Ossium

2021-01-07

Abstract excerpt

Fibrogenesis imperfecta ossium (FIO) is a rare, metabolic bone disease clinically characterized by generalized bone pain and fragility fractures in both the axial and appendicular skeleton. The etiology of the disease is unknown and the pathogenesis is poorly understood. In this disorder, collagen arrangement in the bone is disorganized , and causes abnormalities in the organic bone matrix. Genetic cues causing th...

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Literature Corpus work: 2cde7ab9-6427-54aa-8d30-cb23526d609f
DOI: 10.21203/rs.3.rs-138783/v1

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