Article

The non-coding RNA miR-17~92 is a central mediator of T cell activation

2020-10-13

Abstract excerpt

<h4>Summary</h4> T cell activation is paramount for productive adaptive immune responses. CD28 is a key clinically targeted immunoregulatory receptor because it provides the prototypical costimulatory signal required for T cell activation. Therefore, a precise understanding of the molecular consequences of CD28 costimulation has direct therapeutic relevance. Here, we uncover that the microRNA cluster miR-17~92 is...

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Literature Corpus work: 2c8fc19e-3ee4-51e0-9f0d-a40c1f70bc26
DOI: 10.1101/2020.10.13.336537

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