Article

Liver-Specific Nanoparticle-Mediated Delivery and MMP-Triggered Release of Veratridine, a Potent Pro-Apoptotic Molecule, to Effectively Target Metastatic Colorectal Cancer

2025-08-19

Abstract excerpt

Despite considerable advances to improve colorectal cancer (CRC) survival over the last decade, therapeutic challenges remain due to the rapid metastatic dissemination of primary tumors. Nearly 50% of colorectal cancer (CRC) patients develop liver metastases. This shows the pressing need to develop more effective targeted therapies to decrease the high mortality rates associated with metastatic disease. This study...

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Literature Corpus work: 2c331656-291f-5670-a81f-fa65765424f0
DOI: 10.20944/preprints202508.1367.v1

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