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Cell Atlas of The Human Fovea and Peripheral Retina

17 Jun 2020

Abstract excerpt

Most irreversible blindness results from retinal disease. To advance our understanding of the etiology of blinding diseases, we used single-cell RNA-sequencing (scRNA-seq) to analyze the transcriptomes of ~85,000 cells from the fovea and peripheral retina of seven adult human donors. Utilizing computational methods, we identified 58 cell types within 6 classes: photoreceptor, horizontal, bipolar, amacrine,...

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PMID: 32555229
DOI: 10.1038/s41598-020-66092-9

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