Article

Dissection-independent production of a protective whole-sporozoite malaria vaccine

2020-06-22

Abstract excerpt

Complete protection against human malaria challenge has been achieved using infected mosquitoes as the delivery route for immunization with Plasmodium parasites. Strategies seeking to replicate this efficacy with either a manufactured whole-parasite or subunit vaccine, however, have shown only limited success. A major roadblock to whole parasite vaccine progress and understanding of the human infective sporozoite...

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Literature Corpus work: 2c2122ea-0644-57a2-ae3b-b946a50ff5be
DOI: 10.1101/2020.06.22.164756

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