Article

A single-cell eQTL atlas of the human cerebellum reveals vulnerability of oligodendrocytes in essential tremor

2024-06-11

Abstract excerpt

<title>Abstract</title> <p>Essential tremor (ET) is a movement disorder characterized by an upper-limb postural and action tremor. It is one of the most common neurological disorders, affecting 1% of the worldwide population. Despite strong evidence for genetic factors driving the aetiology of ET, the underlying pathophysiology remains poorly understood. To understand the effects of genetic risk factors in ET on...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1c9b0ce0-97aa-576d-becf-1e132f59afe5
DOI: 10.21203/rs.3.rs-4487252/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A single-cell eQTL atlas of the human cerebellum reveals vulnerability of oligodendrocytes in essential tremorDOI 10.21203/rs.3.rs-4487252/v1Read

A single-cell eQTL atlas of the human cerebellum reveals vulnerability of oligodendrocytes in essential tremorSemantic proximity Read

Single-cell expression QTL analyses of the human cerebellum reveal vulnerability of oligodendrocytes in essential tremor.Semantic proximity Read

Genome-Wide Meta-Analysis Identifies 47 Novel Loci and Links Essential Tremor to Ventral Diencephalon and Cerebellum MorphometrySemantic proximity Read

Multi-omics integration of the phenome, transcriptome and genome highlights genes and pathways relevant to essential tremorSemantic proximity Read

Association of Essential Tremor With Novel Risk Loci: A Genome-Wide Association Study and Meta-analysis.Semantic proximity Read

Essential tremor.Semantic proximity Read

Essential tremor: genetic updateSemantic proximity Read

GWAS meta-analysis reveals key risk loci in essential tremor pathogenesis.Semantic proximity Read

Insights into Essential Tremor and Essential Tremor-Plus from Common VariantsSemantic proximity Read

<span data-contrast="auto">Essential Tremor: A Focused Literature Review on its Pathophysiology, Neurophysiology, Etiology, and Management<span data-ccp-props="{"201341983":0,"335551550":2,"335551620":2,"335559739":160,"335559740":303}">Semantic proximity Read

Exome-wide rare variant analysis in familial essential tremor.Semantic proximity Read

Genetic Identification of Cell Types Underlying Brain Complex Traits Yields Novel Insights Into the Etiology of Parkinson’s DiseaseSemantic proximity Read