Article
Management of genetic epilepsies: From empirical treatment to precision medicine.
Pharmacological research - 1 May 2016
Striano Pasquale, Vari Maria Stella, Mazzocchetti Chiara, Verrotti Alberto, Zara Federico
Abstract excerpt
Despite the over 20 antiepileptic drugs (AEDs) now licensed for epilepsy treatment, seizures can be effectively controlled in about ∼70% of patients. Thus, epilepsy treatment is still challenging in about one third of patients and this may lead to a severe medically, physically, and socially disabling condition. However, there is clear evidence of heterogeneity of response to existing AEDs and a significant unmet...
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