Article

<i>De novo</i> non-compartmentalized microorganism for directed evolution of nanobodies

2024-11-28

Abstract excerpt

The creation of de novo microorganisms is a fascinating task, and microorganisms offer a wide range of applications for humanity. Herein, we designed a de novo microorganism, termed Syn-phage, as an artificial unencapsulated mimic of naturally occurring phage capable of evolving nanobodies with improved properties. Syn-phage composes unified genomic and phenotypic materials with phenotypic proteins encoded from...

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Literature Corpus work: 2ba1c610-8d1e-50b3-bf49-3dfa41a5aa56
DOI: 10.1101/2024.11.27.625622

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