Article

Cucurbitacin E reduce IL-1β-induced inflammation and cartilage degeneration in osteoarthritic chondrocytes by inhibiting the PI3K/AKT pathway

2023-09-25

Abstract excerpt

<title>Abstract</title> <p>Osteoarthritis (OA) is a degenerative joint disease. Cartilage degeneration is the earliest and most important pathological change of osteoarthritis. It is generally considered to be a low-grade inflammatory disease, and persistent inflammation is one of the driving factors of cartilage degeneration. Cucurbitacin E (CuE) is a compound isolated from cucurchinaceae that has been shown to...

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Literature Corpus work: 2b94805b-4576-5f88-a21e-3964aa949049
DOI: 10.21203/rs.3.rs-3332652/v1

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