Article

Correspondence: Recurrent ECSIT mutation encoding V140A triggers hyperinflammation and promotes hemophagocytic syndrome in extranodal NK/T cell lymphoma

2024-09-22

Abstract excerpt

Recurrent somatic mutation in the ECSIT gene encoding p.V140A was reported in 19.3% (17/88) extranodal natural-killer/T cell lymphoma (ENKTL) and was associated with hemophagocytic syndrome (HPS). However, another cohort of similar geographical descent also had the ECSIT V140A mutation as germline in 20.0% (5/25) of ENKTL and none were somatic. The reanalysis of published data revealed that the reported somatic EC...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2b826f4a-3525-56d9-8979-f7396245f26f
DOI: 10.1101/2024.09.19.24314011

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Correspondence: Recurrent ECSIT mutation encoding V140A triggers hyperinflammation and promotes hemophagocytic syndrome in extranodal NK/T cell lymphomaDOI 10.1101/2024.09.19.24314011Read

Recurrent ECSIT mutation encoding V140A triggers hyperinflammation and promotes hemophagocytic syndrome in extranodal NK/T cell lymphoma.Semantic proximity Read

Frequent mutations in HLA and related genes in extranodal NK/T cell lymphomas.Semantic proximity Read

Mutational profile and EBV strains of extranodal NK/T-cell lymphoma, nasal type in Latin America.Semantic proximity Read

Genetic and Clinical Distinction between Aggressive NK-cell Leukemia and Extranodal NK/T-cell Lymphoma with Bone Marrow InvolvementSemantic proximity Read

TMC8 mutation in a Turkish family with epidermodysplasia verruciformis including laryngeal papilloma and recurrent skin carcinoma.Semantic proximity Read

Correspondence: Recurrent <i>GNAQ</i> mutation encoding T96S in natural killer/T cell lymphomaSemantic proximity Read

Identification of LCK mutation in a family with atypical epidermodysplasia verruciformis with T-cell defects and virus-induced squamous cell carcinoma.Semantic proximity Read

A 9-year-old patient with indolent NK cell lymphoproliferative disorder: What role does an inherited SESN3 mutation play?Semantic proximity Read

Inherited Genetic Susceptibility to Nonimmunosuppressed Epstein-Barr Virus-associated T/NK-cell Lymphoproliferative Diseases in Chinese Patients.Semantic proximity Read

Analysis of latent T-cell epitopes in Epstein-Barr virus isolated from extranodal nasal-type natural killer/T-cell lymphoma in Taiwanese population.Semantic proximity Read

A distinct variant of Epidermodysplasia verruciformis in a Turkish family lacking EVER1 and EVER2 mutations.Semantic proximity Read

An Angioimmunoblastic T-cell Lymphoma Patient Presented as Persistent Hypereosinophilia With a Novel RHOA Mutation Encoding p. Ala161GluSemantic proximity Read