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Inherited Genetic Susceptibility to Nonimmunosuppressed Epstein-Barr Virus-associated T/NK-cell Lymphoproliferative Diseases in Chinese Patients.

Current medical science - 1 Jun 2021

Guan Yu-Qi, Shen Ke-Feng, Yang Li, Cai Hao-Dong, Zhang Mei-Lan, Wang Jia-Chen, Long Xiao-Lu, Xiong Jie, Gu Jia, Zhang Pei-Ling, Xiao Min, Zhang Wei, Zhou Jian-Feng

Abstract excerpt

Epstein-Barr virus (EBV) T/NK-cell lymphoproliferative diseases are characterized by clonal expansion of EBV-infected T or NK cells, including chronic active EBV infection of T/NK-cell type (CAEBV+T/NK), EBV-associated hemophagocytic lymphohistiocytosis (EBV+HLH), extranodal NK/T-cell lymphoma of nasal type (ENKTL), and aggressive NK-cell leukemia (ANKL). However, the role of inherited genetic variants to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34170459
DOI: 10.1007/s11596-021-2375-5

Genes

ITK
LYST
PRF1
UNC13D

Provenance

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