Article
Identification of LCK mutation in a family with atypical epidermodysplasia verruciformis with T-cell defects and virus-induced squamous cell carcinoma.
The British journal of dermatology - 1 Dec 2016
Li S-L, Duo L-N, Wang H-J, Dai W, Zhou E-Y H, Xu Y-N, Zhao T, Xiao Y-Y, Xia L, Yang Z-H, Zheng L-T, Hu Y-Y, Lin Z-M, Wang H-N, Gao T-W, Ma C-L, Yang Y, Li C-Y
Abstract excerpt
BACKGROUND: Inherited epidermodysplasia verruciformis (EV) is a rare skin disorder characterized by susceptibility to specific types of human papilloma virus (HPV) and is strongly associated with skin carcinomas. Inactivating mutations in EVER1/EVER2 account for most cases of EV. However, more phenotypes related to but distinct from EV have been reported with an immunodeficiency state but without EVER1/EVER2...
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