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Article

Molecular characterization of the monoclonal antibodies composing ZMAb: a protective cocktail against Ebola virus.

Scientific reports - 6 Nov 2014

Audet Jonathan, Wong Gary, Wang Han, Lu Guangwen, Gao George F, Kobinger Gary, Qiu Xiangguo

Abstract excerpt

Ebola virus (EBOV) causes severe viral hemorrhagic fever in humans and non-human primates, with a case fatality rate of up to 88% in human outbreaks. Over the past 3 years, monoclonal antibody (mAb) cocktails have demonstrated high efficacy as treatments against EBOV infection. One such cocktail is ZMAb, which consists of three mouse antibodies, 1H3, 2G4, and 4G7. Here, we present the epitope binding properties...

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Share to Antibodies, Viral
Share to Antigen-Antibody Complex

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antigen-Antibody Reactions

Share to Ebolavirus

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Share to Hemorrhagic Fever, Ebola

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Source

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Identifiers

PMID: 25375093
DOI: 10.1038/srep06881
PMCID: PMC5381473

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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