Article
Regulation of neural gene expression by estrogen receptor alpha
2020-10-21
Abstract excerpt
The transcription factor estrogen receptor α (ERα) is a principal regulator of sex differences in the vertebrate brain and can modulate mood, behavior, and energy balance in females and males. However, the genes regulated by ERα in the brain remain largely unknown. Here we reveal the genomic binding of ERα within a sexually dimorphic neural circuit that regulates social behaviors. We profiled gene expression and c...
Topics
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- Cytokine Signaling Pathways and Interactions
- Endometriosis Research and Treatment
- Estrogen and related hormone effects
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Hypothalamic control of reproductive hormones
- Menopause: Health Impacts and Treatments
- Neuroendocrine regulation and behavior
- Stress Responses and Cortisol
Identifiers and source
- Literature Corpus work
- 2ae5db6e-fc08-56b5-affe-435f489f39d6
- DOI
- 10.1101/2020.10.21.349290
