Article
Transcriptome analysis reveals high tumor heterogeneity with respect to re-activation of stemness and proliferation programs
2021-09-03
Abstract excerpt
Significant alterations in signaling pathways and transcriptional regulatory programs together represent major hallmarks of many cancers. These, among all, include the reactivation of stemness, which is registered by the expression of pathways that are active in the embryonic stem cells (ESCs). Here, we assembled gene sets that reflect the stemness and proliferation signatures and used them to analyze a large pane...
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Identifiers and source
- Literature Corpus work
- 2ae2ef65-31bc-586a-841c-61d428103cc4
- DOI
- 10.1101/2021.09.02.458724