Article

Genomic landscapes of canine splenic angiosarcoma (hemangiosarcoma) contain extensive heterogeneity within and between patients

2020-11-17

Abstract excerpt

<h4>ABSTRACT</h4> Cancer genomic heterogeneity presents significant challenges for understanding oncogenic processes and for cancer’s clinical management. Variation in driver mutation frequency between patients with the same tumor type as well as within individual patients’ cancers can limit the power of mutations to serve as diagnostic, prognostic, and predictive biomarkers. We have characterized genomic heterog...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2a8f6eb1-b388-50eb-821b-f82dad3b57ae
DOI: 10.1101/2020.11.15.380048

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genomic landscapes of canine splenic angiosarcoma (hemangiosarcoma) contain extensive heterogeneity within and between patientsDOI 10.1101/2020.11.15.380048Read

Genomic landscapes of canine splenic angiosarcoma (hemangiosarcoma) contain extensive heterogeneity within and between patients.Semantic proximity Read

Identification of genomic alterations with clinical impact in canine splenic hemangiosarcomaSemantic proximity Read

Comparative Genomics Reveals Shared Mutational Landscape in Canine Hemangiosarcoma and Human AngiosarcomaSemantic proximity Read

Real-world evidence couples genomic biomarkers with therapeutic outcomes for canine hemangiosarcomaSemantic proximity Read

Identification of genomic alterations with clinical impact in canine splenic hemangiosarcomaSemantic proximity Read

Comparison of the oncogenomic landscape of canine and feline hemangiosarcoma shows novel parallels with human angiosarcoma.Semantic proximity Read

Molecular subtypes in canine hemangiosarcoma reveal similarities with human angiosarcoma.Semantic proximity Read

Actionable mutations in canine hemangiosarcoma.Semantic proximity Read

Genomic analysis reveals shared genes and pathways in human and canine angiosarcomaSemantic proximity Read

Genomically Complex Human Angiosarcoma and Canine Hemangiosarcoma Establish Convergent Angiogenic Transcriptional Programs Driven by Novel Gene FusionsSemantic proximity Read

Feasibility of circulating tumor DNA analysis in dogs with naturally occurring malignant and benign splenic lesions.Semantic proximity Read