Article
Feasibility of circulating tumor DNA analysis in dogs with naturally occurring malignant and benign splenic lesions.
Scientific reports - 15 Apr 2022
Favaro Patricia Filippsen, Stewart Samuel D, McDonald Bradon R, Cawley Jacob, Contente-Cuomo Tania, Wong Shukmei, Hendricks William P D, Trent Jeffrey M, Khanna Chand, Murtaza Muhammed
Abstract excerpt
Comparative studies of naturally occurring canine cancers have provided new insight into many areas of cancer research. Development and validation of circulating tumor DNA (ctDNA) analysis in pet dogs can help address diagnostic needs in veterinary as well as human oncology. Dogs have high incidence of naturally occurring spontaneous cancers, demonstrate molecular heterogeneity and clonal evolution during...
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