Article
Actionable mutations in canine hemangiosarcoma.
PloS one - 1 Jan 2017
Wang Guannan, Wu Ming, Maloneyhuss Martha A, Wojcik John, Durham Amy C, Mason Nicola J, Roth David B
Abstract excerpt
BACKGROUND: Angiosarcomas (AS) are rare in humans, but they are a deadly subtype of soft tissue sarcoma. Discovery sequencing in AS, especially the visceral form, is hampered by the rarity of cases. Most diagnostic material exists as archival formalin fixed, paraffin embedded tissue which serves as a poor source of high quality DNA for genome-wide sequencing. We approached this problem through comparative...
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