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Induction of promyelocytic leukemia zinc finger protein by miR-200c-3p restores sensitivity to anti-androgen therapy in androgen-refractory prostate cancer and inhibits the cancer progression via down-regulation of integrin α3β4

2022-10-20

Abstract excerpt

<h4>Purpose: </h4> Androgen-refractory prostate cancer (ARPC) is one of the aggressive human cancers with metastatic capacity and resistance to androgen deprivation therapy (ADT). The present study investigated the genes responsible for ARPC progression and ADT resistance, and their regulatory mechanisms. Methods Transcriptome analysis, co-immunoprecipitation, confocal microscopy, and FACS analysis were performed...

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Literature Corpus work
2a71b4f1-29f2-59b7-9896-ffe09ec7c7ab
DOI
10.21203/rs.3.rs-2171149/v1
Open publication

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Induction of promyelocytic leukemia zinc finger protein by miR-200c-3p restores sensitivity to anti-androgen therapy in androgen-refractory prostate cancer and inhibits the cancer progression via down-regulation of integrin α3β4DOI 10.21203/rs.3.rs-2171149/v1
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