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WGCNA Co-Expression Network Analysis Reveals LncRNA LINC00313 Functions as A ceRNA to Regulate PTEN-Mediated PI3K/AKT Signaling Pathway by Sponging miR-19a-3p in Docetaxel-Resistant Prostate Cancer Cells

2020-10-21

Abstract excerpt

<h4>Background: </h4> Docetaxel is the preferred chemotherapeutic agent for patients with hormone-refractory PCa. LncRNAs play important roles in the development of docetaxel resistance in patients with PCa. We evaluated the effects of the lncRNA LINC00313 on growth and metastasis in docetaxel-resistant PCa cells, and the molecular mechanisms underlying these effects. <h4>Methods: </h4>: The mRNA dataset (GSE10212...

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Literature Corpus work: b44f5beb-50e7-5a29-8c2b-3da9cddbd772
DOI: 10.21203/rs.3.rs-94032/v1

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