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Cross-species scRNA-seq reveals the cellular landscape of retina and early alterations in type 2 diabetes mice

4 Jun 2023

Abstract excerpt

Single-cell RNA sequencing (scRNA-seq) analysis have provided an unprecedented resolution for the studies on diabetic retinopathy (DR). However, the early changes in the retina in diabetes remain unclear. A total of 8 human and mouse scRNA-seq datasets, containing 276,402 cells were analyzed individually to comprehensively delineate the retinal cell atlas. The neural retinas were isolated from the type 2 diabetes...

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Share to Neuroinflammation and Neurodegeneration Mechanisms
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PMID: 37279838
DOI: 10.1016/j.ygeno.2023.110644

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