Article

Multi-omics analysis Identifies PTTG1 as a prognostic biomarker associated with immunotherapy and chemotherapy resistance

2024-09-16

Abstract excerpt

<title>Abstract</title> <p>Background Pituitary tumor-transforming gene 1 (PTTG1) is an important gene in tumour development. However, the relevance of PTTG1 in tumour prognosis, immunotherapy response, and medication sensitivity in human pan-cancer has to be determined. Methods TIMER, GEPIA, the human protein atlas, GEPIA, TISCH2, and cBioportal examined the gene expression, protein expression, prognostic valu...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2a389a97-a168-59b9-852d-f9909617f5d1
DOI: 10.21203/rs.3.rs-4923978/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Multi-omics analysis Identifies PTTG1 as a prognostic biomarker associated with immunotherapy and chemotherapy resistanceDOI 10.21203/rs.3.rs-4923978/v1Read

A Comprehensive Pan-Cancer Analysis for Pituitary Tumor-Transforming Gene 1Semantic proximity Read

Pituitary tumor-transforming gene 1 and endocrine cancers: an up-to-date review through history, current insights and future perspectivesSemantic proximity Read

Clinical significance and potential regulatory mechanism of overexpression of pituitary tumor-transforming gene transcription factor in bladder cancerSemantic proximity Read

Integrated proteogenomic characterization across major histological types of pituitary neuroendocrine tumorsSemantic proximity Read

Increased expression of pituitary tumor-transforming gene (PTTG)-1 is correlated with poor prognosis in glioma patientsSemantic proximity Read

From Genes to Therapy: Pituitary Adenomas in the Era of Precision MedicineSemantic proximity Read

Overexpressing PTTG Family Genes Predict Poor Prognosis in KIRCSemantic proximity Read

Are PTTG1 variants associated with tumor characteristics and p53/Ki-67 expression in pituitary neuroendocrine tumors.Semantic proximity Read

The DLK1/MEG3 Locus is Related to the Differentiation of Pituitary Neuroendocrine TumorsSemantic proximity Read

Machine learning to comprehensively reveal signature genes and regulatory mechanisms in pituitary tumorsSemantic proximity Read

Gene-interaction perturbation network analysis identifies distinct subtypes and actionable targets for aggressive thyroid cancer: an integrative multi-omics and machine learning approach for precise medicineSemantic proximity Read

Tumor Immune Microenvironment in Pituitary Neuroendocrine Tumors (PitNETs): Increased M2 Macrophage Infiltration and PD-L1 Expression in PIT1-lineage SubsetSemantic proximity Read