Article

Tumor Immune Microenvironment in Pituitary Neuroendocrine Tumors (PitNETs): Increased M2 Macrophage Infiltration and PD-L1 Expression in PIT1-lineage Subset

2023-06-01

Abstract excerpt

<h4>Purpose: </h4> Tumor immune microenvironment in PitNETs and application of current immunotherapy for refractory PitNETs remains debated. We aim to evaluate the immune landscape in different lineages of PitNETs and determine the potential role of pituitary transcription factors in reshaping the TIME, thus promoting the application of current immunotherapy for aggressive and metastatic PitNETs. Methods Immunocy...

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Literature Corpus work: fa32e809-7880-524c-bde7-2f6a276d4062
DOI: 10.21203/rs.3.rs-3001593/v1

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