Article
Enhanced glutamatergic phenotype of mesencephalic dopamine neurons after neonatal 6-hydroxydopamine lesion.
Neuroscience - 22 Sept 2008
Dal Bo G, Bérubé-Carrière N, Mendez J A, Leo D, Riad M, Descarries L, Lévesque D, Trudeau L-E
Abstract excerpt
There is increasing evidence that a subset of midbrain dopamine (DA) neurons uses glutamate as a co-transmitter and expresses vesicular glutamate transporter (VGLUT) 2, one of the three vesicular glutamate transporters. In the present study, double in situ hybridization was used to examine tyrosine hydroxylase (TH) and VGLUT2 mRNA expression during the embryonic development of these neurons, and postnatally, in...
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