Article

A Two-Step Activation Mechanism Enables Mast Cells to Differentiate their Response between Extracellular and Invasive Enterobacterial Infection

2023-09-01

Abstract excerpt

Mast cells (MCs) localize to mucosal tissues and contribute to innate immune defenses against infection. How MCs sense, differentiate between, and respond to bacterial pathogens remains a topic of ongoing debate. Using the prototype enteropathogen Salmonella Typhimurium ( S .Tm) and other closely related enterobacteria, we here demonstrate that MCs can regulate their cytokine secretion response to distinguish be...

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Literature Corpus work: 29ad37d2-1c5b-5ea0-a02c-240e16a1e2b1
DOI: 10.1101/2023.08.31.555657

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