Article

Human parvovirus B19 interacts with globoside under acidic conditions as an essential step in endocytic trafficking

2021-03-02

Abstract excerpt

The glycosphingolipid (GSL) globoside (Gb4) is essential for parvovirus B19 (B19V) infection. Historically considered the cellular receptor of B19V, the role of Gb4 and its interaction with B19V are controversial. In this study, we applied artificial viral particles, genetically modified cells, and specific competitors to address the interplay between the virus and the GSL. Our findings demonstrate that Gb4 is not...

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Literature Corpus work: 299daf0c-1190-5796-a518-c7e5ada5c34c
DOI: 10.1101/2021.03.02.433539

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