Article

Most Japanese individuals are genetically predisposed to recognize an immunogenic protein fragment shared between COVID-19 and common cold coronaviruses

2021-03-10

Abstract excerpt

In the spring of 2020, we and others hypothesized that T cells in COVID-19 patients may recognize identical protein fragments shared between the coronaviruses of the common cold and COVID-19 and thereby confer cross-virus immune memory. Here, we look at this issue by screening studies that, since that time, have experimentally addressed COVID-19 associated T cell specificities. Currently, the identical T cell epit...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 29979840-cff7-5c42-adf1-4de9bf18de5a
DOI: 10.12688/f1000research.51479.1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Most Japanese individuals are genetically predisposed to recognize an immunogenic protein fragment shared between COVID-19 and common cold coronavirusesDOI 10.12688/f1000research.51479.1Read

Broadly-recognized, cross-reactive SARS-CoV-2 CD4 T cell epitopes are highly conserved across human coronaviruses and presented by common HLA allelesSemantic proximity Read

HLA-A*11:01:01:01, HLA*C*12:02:02:01-HLA-B*52:01:02:02, age and sex are associated with severity of Japanese COVID-19 with respiratory failureSemantic proximity Read

Broadly recognized, cross-reactive SARS-CoV-2 CD4 T cell epitopes are highly conserved across human coronaviruses and presented by common HLA alleles.Semantic proximity Read

HLA-DQA1*01:03 and DQB1*06:01 are risk factors for severe COVID-19 pneumonia.Semantic proximity Read

A web-based genome-wide association study reveals the susceptibility loci of common adverse events following COVID-19 vaccination in the Japanese population.Semantic proximity Read

HLA-DQ2/8 and COVID-19 in celiac disease: Boon or BaneSemantic proximity Read

Distribution of HLA allele frequencies in 82 Chinese individuals with coronavirus disease-2019 (COVID-19).Semantic proximity Read

Can the protection be among us? Previous viral contacts and prevalent HLA alleles avoiding an even more disseminated COVID-19 pandemicSemantic proximity Read

High frequencies of alpha common cold coronavirus/SARS-CoV-2 cross-reactive functional CD4+ and CD8+ memory T cells are associated with protection from symptomatic and fatal SARS-CoV-2 infections in unvaccinated COVID-19 patientsSemantic proximity Read

Identification of susceptibility loci for adverse events following COVID-19 vaccination in the Japanese population: A web-based genome-wide association studySemantic proximity Read

Association of HLA-DRB1*09:01 with severe COVID-19.Semantic proximity Read

COVID-19禍の日本社会と心理──2020年3月下旬実施調査に基づく検討──Semantic proximity Read