Article

Dietary fiber controls blood pressure and cardiovascular risk by lowering large intestinal pH and activating the proton-sensing receptor GPR65

2022-11-18

Abstract excerpt

High blood pressure (BP) is the most common cause of death globally, due to increasing the risk of cardiovascular diseases. Dietary fiber regulates BP through gut microbial production of acidic metabolites known as short-chain fatty acids (SCFAs). The specific mechanisms of how SCFAs regulate BP are still emerging. In a phenome-wide association study, we identified that the proton-sensing G-protein-coupled recepto...

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Literature Corpus work: 29802f51-8037-5212-9924-8c25491db583
DOI: 10.1101/2022.11.17.516695

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Dietary fiber controls blood pressure and cardiovascular risk by lowering large intestinal pH and activating the proton-sensing receptor GPR65DOI 10.1101/2022.11.17.516695Read

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