Article
Genomic Determinants of Hypertension With a Focus on Metabolomics and the Gut Microbiome.
American journal of hypertension - 21 May 2020
Louca Panayiotis, Menni Cristina, Padmanabhan Sandosh
Abstract excerpt
Epidemiologic and genomic studies have progressively improved our understanding of the causation of hypertension and the complex relationship with diet and environment. The majority of Mendelian forms of syndromic hypotension and hypertension (HTN) have all been linked to mutations in genes whose encoded proteins regulate salt-water balance in the kidney, supporting the primacy of the kidneys in blood pressure...
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