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<i>Drosophila melanogaster</i> model of RVCL-S demonstrates age dependent disease progression

2025-11-10

Abstract excerpt

Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations (RVCL-S) is a disease that causes deterioration of small vessels, affecting various organs: eyes, brain, liver, and others. The RVCL-S carriers have lower life expectancy. There is no cure available to date. The disease has been linked to mutations in TREX1 gene disrupting its cytoplasmic localization. To facilitate the disease mech...

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Identifiers and source

Literature Corpus work
297521ac-8db4-5614-99f2-00edadc4582c
DOI
10.1101/2025.11.10.687584
Open publication

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<i>Drosophila melanogaster</i> model of RVCL-S demonstrates age dependent disease progressionDOI 10.1101/2025.11.10.687584
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