Article

Clinical quality in cancer research - Strategy to assess data integrity of germline variants inferred from tumor-only testing sequencing data

2021-08-04

Abstract excerpt

<title>Abstract</title> <p>In the majority of cancers, pathogenic variants are only found at the level of the tumor; however, an unusual number of cancers and/or diagnoses at an early age in a single family may suggest a genetic predisposition. Predisposition plays a major role in about 5 to 10% of adult cancers and in certain childhood tumors. As access to genomic testing for cancer patients continues to expand,...

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Literature Corpus work: 2cd27526-092e-5fe1-906a-d719389efe62
DOI: 10.21203/rs.3.rs-418086/v2

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